Customization: | Available |
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CAS No.: | 65277-42-1 |
Formula: | C26h28cl2n4o4 |
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Product Name: | Ketoconazole |
Synonyms: | ,3-dioxolan-4-yl)methoxy)phenyl)-,cis-;fungarest;fungoral;ketoconazol;ketoderm;ketoisdin;kw-1414;nizoral |
CAS: | 65277-42-1 |
MF: | C26H28Cl2N4O4 |
MW: | 531.43 |
EINECS: | 265-667-4 |
Mol File: | 65277-42-1.mol |
Ketoconazole Chemical Properties |
Melting point | 148-152 °C |
Boiling point | 753.4±60.0 °C(Predicted) |
density | 1.4046 (rough estimate) |
refractive index | -10.5 ° (C=0.4, CHCl3) |
Fp | 9ºC |
storage temp. | 2-8°C |
solubility | MEOH, soluble50mg/mL |
pka | pKa 3.25/6.22(H2O,t =25,I=0.025) (Uncertain) |
form | Off-white solid |
color | white to light yellow |
optical activity | [α]20/D -1 to 1°, c = 4 in MEOH |
Water Solubility | Soluble in DMSO, ethanol, water |
BCS Class | 2 |
Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months. |
InChIKey | XMAYWYJOQHXEEK-OZXSUGGESA-N |
LogP | 4.350 |
CAS DataBase Reference | 65277-42-1(CAS DataBase Reference) |
Standard | Medical standard |
Shelf life | 2 years |
Storage | should be stored in a well-closed container at low temperature, keep away from moisture, heat and light. |
Test Item | Standard: USP |
Identification | IR spectrum similar to that of RS |
HPLC retention time similar to that of RS | |
Related substance | Total impurities: NMT0.3% |
Single impurity: NMT0.1% | |
Heavy metals | NMT 10ppm |
Loss on drying | NMT0.5% |
Residue on ignition | NMT0.1% |
Assay | 98.5%-101.0% |